Noticing that the waist circumference on average went down on the peppermint group (85.17 -> 84.61) while the placebo group it went up (88.33 -> 88.65)? Also the resting heart rate dropped for the peppermint group. My initial suspicion is that the peppermint group coincidentally was also the 'got in better shape' group. Maybe the peppermint helped, but for relatively small groups that also seem to be improving waist circumference and heart rates likely due to good diet and exercise, I'm not convinced the peppermint did jack shit. More investigation needed! Would be awesome if it helped though!
There has been some research on spearmint suggesting anti-androgen effects in PCOS, which is a bit unexpected to me as I wouldn't expect mint-family herbs to have much hormone modulating effect at all. I would imagine there to be similarities in profile between spearmint and peppermint so perhaps a related mechanism is involved, although I would probably expect the opposite outcome as a naive layperson. But I haven't closely evaluated the paper nor do I know whether there's been much else suggesting this
It is important to remember that herbs are difficult to study in this setting compared with isolated compounds -- likely because their pharmacological and chemical compositions are sensitive to many factors: hour and season of harvest, form consumed (raw powder, alcohol extract, cold water infusion, fat emulsion, hot water infusion, combustion, pyrolysis, essential oil), part consumed (leaf, root, flower, seed), among staggeringly many others. Anyone with experience consuming cannabis or coffee can probably testify to the above
Not to mention that the pharmacologically active compounds in many plants are far from being comprehensively understood, let alone their interactions and dynamics
This isn't to say that every claim about herbs is to be taken seriously. My point here is more that there is no good reason to dismiss the herb itself as a cause yet simply because it's an herb and a fairly mundane one at that. There are easy examples of herbs which have pronounced physiological effects, used for recreation, performance enhancement, as literal poison, to induce labor, to thin the blood -- among others.
Peppermint oil has traditionally been used in India for digestion, so you may be on to something. I remember this particular brand growing up: https://www.amazon.com/clp/B001NQ7S9G (no relation).
But weight/mass didn't change one bit (okay exaggeration, but not by much), so maybe peppermint helps relieve gas. Who knows? There's a lot that this data could mean, and no simple way to figure it out.
I'd think weight could be causal for hypertension result or sentiment over health measurement could have been causal for weight or the study could just be too small.
When you say weight, do you really mean obesity? And if you are talking about weight, is it likely that people who live in low gravity environments will have fewer hypertension problems?
I'm guessing that this number is the result of the average of "x" people in the study, and not an individual measurement. But, yeah, I see what that looks like.
Peppermint group N=20. Mkay. 2 of those lost to followup, one because they didn't like the taste (control group got peppermint cordial). The result might be real but needs followup before we all starting gulping down peppermint oil.
I was surprised by this too. From a background in writing code to control precision pumps, I have a good idea of what 50 µL looks like and it seemed like an awfully small amount. But I don't know how concentrated the oil is.
FWIW, I had an Indian co-worker who took peppermint oil frequently and said that it was very good for his upset stomach.
From PLOS One as well! I remember in college, I was taking a bio class that taught how to read journal articles...and a psych class that was assigning them. Psych class assigned almost solely PLOS One articles...which didn't survive the criticism I was being taught in the bio class lmao
>Perhaps inspired by that experimental ethos, customers have discovered their own unusual uses in the years since Emanuel started mixing gallons of peppermint castile soap out of his Pershing Square tenement apartment in 1948. [...]
>David, Mike and Lisa Bronner grew up in Glendale, not giving much thought to the prospect of one day taking over the family business and generally regarding their grandfather as a bewildering figure.
>“My granddad was always talking about uniting ‘Spaceship Earth,’ and it was kind of sailing over our heads,” David said.
>“He’d be talking to us as if we were all PhD students in religious studies,” Mike said of visits to Emanuel’s home when the siblings were in elementary school. “He was blind, and every once in a while he would say, ‘Are you there?’ and we’d be like, “All-one, Grandpa!’ And he’d be like, ‘Very good. OK, I want you to recite the peppermint bottle.’”
>The label on the quart size of the Lavender Pure-Castile Magic Soap holds the greatest insight for me into his motivations and goals. The Peppermint label records the tenets of his Moral ABC, his guidelines for humanity to find unity and a path forward. But it is the Lavender quart that hosts his poetry, and in that I see his heart. [...]
>"To keep my health! To do my work! To love, to live!"
>"Great peace is found in little busyness."
>"Work well yourself and work for all."
>"Til we rally, raise, unite!"
>"All-One-God-Faith, All-One! Unite!"
>"Lives of great men all remind us we can make our lives sublime."
>"Life is real! Life is earnest! And the grave is not its goal."
>"Let us then be up and doing ... still achieving, still pursuing"
>"In all we do, let us be generous, fair & loving to Spaceship Earth and all its inhabitants."
Noticing that the waist circumference on average went down on the peppermint group (85.17 -> 84.61) while the placebo group it went up (88.33 -> 88.65)? Also the resting heart rate dropped for the peppermint group. My initial suspicion is that the peppermint group coincidentally was also the 'got in better shape' group. Maybe the peppermint helped, but for relatively small groups that also seem to be improving waist circumference and heart rates likely due to good diet and exercise, I'm not convinced the peppermint did jack shit. More investigation needed! Would be awesome if it helped though!
There has been some research on spearmint suggesting anti-androgen effects in PCOS, which is a bit unexpected to me as I wouldn't expect mint-family herbs to have much hormone modulating effect at all. I would imagine there to be similarities in profile between spearmint and peppermint so perhaps a related mechanism is involved, although I would probably expect the opposite outcome as a naive layperson. But I haven't closely evaluated the paper nor do I know whether there's been much else suggesting this
It is important to remember that herbs are difficult to study in this setting compared with isolated compounds -- likely because their pharmacological and chemical compositions are sensitive to many factors: hour and season of harvest, form consumed (raw powder, alcohol extract, cold water infusion, fat emulsion, hot water infusion, combustion, pyrolysis, essential oil), part consumed (leaf, root, flower, seed), among staggeringly many others. Anyone with experience consuming cannabis or coffee can probably testify to the above
Not to mention that the pharmacologically active compounds in many plants are far from being comprehensively understood, let alone their interactions and dynamics
This isn't to say that every claim about herbs is to be taken seriously. My point here is more that there is no good reason to dismiss the herb itself as a cause yet simply because it's an herb and a fairly mundane one at that. There are easy examples of herbs which have pronounced physiological effects, used for recreation, performance enhancement, as literal poison, to induce labor, to thin the blood -- among others.
https://pubmed.ncbi.nlm.nih.gov/19585478/
Peppermint oil has traditionally been used in India for digestion, so you may be on to something. I remember this particular brand growing up: https://www.amazon.com/clp/B001NQ7S9G (no relation).
But weight/mass didn't change one bit (okay exaggeration, but not by much), so maybe peppermint helps relieve gas. Who knows? There's a lot that this data could mean, and no simple way to figure it out.
I'd think weight could be causal for hypertension result or sentiment over health measurement could have been causal for weight or the study could just be too small.
When you say weight, do you really mean obesity? And if you are talking about weight, is it likely that people who live in low gravity environments will have fewer hypertension problems?
Maybe it helps with weight loss (I wish)
It seems to aid in digestion, soothe upset stomach, so maybe it does.
There are two types of peppermint supplements being sold: mentha pipereta that this study looked at, and mentha arvensis.
I wonder if mentha arvensis has the same effect. Supplements vs mint tea would be another interesting thing to study in future.
Based on your new information, I think it would be good to test the effect of supplemenths vs supplemints.
That is very accurate sphygmomanometry!
I'm guessing that this number is the result of the average of "x" people in the study, and not an individual measurement. But, yeah, I see what that looks like.
Peppermint group N=20. Mkay. 2 of those lost to followup, one because they didn't like the taste (control group got peppermint cordial). The result might be real but needs followup before we all starting gulping down peppermint oil.
>50 µL of supplement diluted into 100 mL of water
pretty tiny amount of peppermint was consumed
I was surprised by this too. From a background in writing code to control precision pumps, I have a good idea of what 50 µL looks like and it seemed like an awfully small amount. But I don't know how concentrated the oil is.
FWIW, I had an Indian co-worker who took peppermint oil frequently and said that it was very good for his upset stomach.
That's enough to turn a whole barrel of water detectably minty.
HN really upvotes some dumb medical articles, come on, n=20 about peppermint?
I've got an n=65 about hibiscus and blood pressure, which has been better well known for awhile. https://www.ars.usda.gov/news-events/news/research-news/2008...
now we need a study of adding Peppermint oil into hybiscus tea.
Silence, we have disruptive direct to consumer peptide startups that need to pump.
From PLOS One as well! I remember in college, I was taking a bio class that taught how to read journal articles...and a psych class that was assigning them. Psych class assigned almost solely PLOS One articles...which didn't survive the criticism I was being taught in the bio class lmao
Doctor Bronner was right!
Peppermint - Pure-Castile Magic Soap: Cool, Refresh, and Awaken with Invigorating Peppermint
https://www.drbronner.com/products/peppermint-pure-castile-l...
Dr. Bronner invented the peppermint oil soap for soiled diapers
https://www.sandiegoreader.com/news/1978/nov/02/cover-look-f...
Created in California: How Dr. Bronner’s became the soap for every subculture
https://www.latimes.com/business/story/2023-07-12/dr-bronner...
>Perhaps inspired by that experimental ethos, customers have discovered their own unusual uses in the years since Emanuel started mixing gallons of peppermint castile soap out of his Pershing Square tenement apartment in 1948. [...]
>David, Mike and Lisa Bronner grew up in Glendale, not giving much thought to the prospect of one day taking over the family business and generally regarding their grandfather as a bewildering figure.
>“My granddad was always talking about uniting ‘Spaceship Earth,’ and it was kind of sailing over our heads,” David said.
>“He’d be talking to us as if we were all PhD students in religious studies,” Mike said of visits to Emanuel’s home when the siblings were in elementary school. “He was blind, and every once in a while he would say, ‘Are you there?’ and we’d be like, “All-one, Grandpa!’ And he’d be like, ‘Very good. OK, I want you to recite the peppermint bottle.’”
Lisa Bronner: The Poetry of the Lavender Label
https://www.lisabronner.com/the-poetry-of-the-lavender-label
>The label on the quart size of the Lavender Pure-Castile Magic Soap holds the greatest insight for me into his motivations and goals. The Peppermint label records the tenets of his Moral ABC, his guidelines for humanity to find unity and a path forward. But it is the Lavender quart that hosts his poetry, and in that I see his heart. [...]
>"To keep my health! To do my work! To love, to live!"
>"Great peace is found in little busyness."
>"Work well yourself and work for all."
>"Til we rally, raise, unite!"
>"All-One-God-Faith, All-One! Unite!"
>"Lives of great men all remind us we can make our lives sublime."
>"Life is real! Life is earnest! And the grave is not its goal."
>"Let us then be up and doing ... still achieving, still pursuing"
>"In all we do, let us be generous, fair & loving to Spaceship Earth and all its inhabitants."
>"We're ALL-ONE OR NONE! ALL-ONE!"
herbal tea is good for you, it seems