43 points | by nogajun 3 hours ago ago
7 comments
It works by causing a release of noadrenalin.
Prediction: It will end up being used by the military and/or fighters to provide instantaneous muscle strength coupled with pain relief from overexertion.
A new class of selective α2B-adrenoceptor antagonist.
Why is this written in such a way to only target cancer patients?
The class of patients most likely to require opioids over long periods of time?
And a class disproportionately insensitive to long term negative side effects.
How is it different from Imiloxan?
Marginally more info, along with the title of the paper, but the doi is broken: https://medicalxpress.com/news/2025-08-discovery-analgesic-p...
There's also the alternative Journavx: https://en.wikipedia.org/wiki/Suzetrigine
It works by causing a release of noadrenalin.
Prediction: It will end up being used by the military and/or fighters to provide instantaneous muscle strength coupled with pain relief from overexertion.
A new class of selective α2B-adrenoceptor antagonist.
Why is this written in such a way to only target cancer patients?
The class of patients most likely to require opioids over long periods of time?
And a class disproportionately insensitive to long term negative side effects.
How is it different from Imiloxan?
Marginally more info, along with the title of the paper, but the doi is broken: https://medicalxpress.com/news/2025-08-discovery-analgesic-p...
There's also the alternative Journavx: https://en.wikipedia.org/wiki/Suzetrigine